PET Imaging of Astrogliosis and Tau Facilitates Diagnosis of Parkinsonian Syndromes
نویسندگان
چکیده
منابع مشابه
Diagnosis and management of atypical parkinsonian syndromes.
Parkinsonian syndromes are characterised by slowness of initiation (akinesia), movement (bradykinesia), and thought (bradyphrenia), tremor at rest (3–5 Hz) and on posture (4–8 Hz), and extrapyramidal rigidity. It is now recognised that a number of diverse pathologies can manifest with these signs making clinical diagnosis complex, especially in early disease (table 1). By searching for certain ...
متن کاملioflupane in diagnosis of parkinsonian syndromes
To cite: Bajaj N, Hauser RA, Grachev ID. J Neurol Neurosurg Psychiatry 2013;84:1288–1295. ABSTRACT The diagnosis of movement disorders including Parkinson’s disease (PD) and essential tremor is determined through clinical assessment. The difficulty with diagnosis of early PD has been highlighted in several recent clinical trials. Studies have suggested relatively high clinical diagnostic error ...
متن کاملPET and SPECT functional imaging studies in Parkinsonian syndromes: from the lesion to its consequences.
Functional imaging techniques provide major insights into understanding the pathophysiology, progression, complications, and differential diagnosis of Parkinson's disease (PD). The dopaminergic system has been particularly studied allowing now early, presymptomatic diagnoses, which is of interest for future neuroprotective strategies. The existence of a compensatory hyperactivity of dopa-decarb...
متن کاملDevelopments in Tau PET Imaging.
ABSTRACT The presence of neurofibrillary tangles in the brain is a hallmark feature of several neurodegenerative diseases termed "tauopathies," including Alzheimer's disease (AD) and the tau molecular subgroup of frontotemporal lobar degeneration (FTLD-tau). Recently, several positron emission tomography (PET) radiopharmaceuticals targeting abnormal conformations of the tau protein have been de...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Aging Neuroscience
سال: 2019
ISSN: 1663-4365
DOI: 10.3389/fnagi.2019.00249